Eli suffers from a rare chronic illness. His family is not sure exactly what triggers it, but exposure to the outside world causes his body to react as if he’s being burned alive. They travel to the remote treatment facility of Dr. Horn who promises a cure through her own method of gene therapy. She’s retrofit an old mansion with a state of the art medical facility, though there are entire sections of the building that remain untouched. Eli becomes convinced there is someone else there, but he is the only patient being treated.